The Perfect 5-Day Rome Itinerary: A Food and Culture Lover’s Guide

Rome is where ancient history, stunning architecture, and world-class cuisine come together in a way that’s impossible to resist. Planning the perfect itinerary can feel overwhelming with so much to see and eat. That’s where I come in! 

Whether you’re a first-time visitor or a returning traveler looking for a deeper dive into the Eternal City, this five-day itinerary balances Rome’s must-see sights with incredible culinary experiences.

Day 1: Arrival & Iconic Landmarks

Morning: Start your Roman adventure with an espresso and cornetto at Sant’Eustachio Il Caffè, a legendary spot near the Pantheon. From here, explore:

• Piazza Navona – One of Rome’s most beautiful squares, featuring Bernini’s Fountain of the Four Rivers.

• The Pantheon – A masterpiece of ancient Roman engineering and home to Raphael’s tomb.

Lunch: Enjoy a classic Roman dish like cacio e pepe or carbonara at Roscioli Salumeria con Cucina, a deli restaurant beloved by locals.

Afternoon: Stroll to the Trevi Fountain and toss in a coin for good luck. Then, walk to the Spanish Steps before indulging in gelato from Gelateria La Romana.

Dinner: Head to Armando al Pantheon, a historic trattoria serving traditional Roman cuisine with a refined touch.

Day 2: Ancient Rome & Jewish Ghetto

Morning: Step back in time at the Colosseum, then explore the Roman Forum, the heart of ancient Rome.

Lunch: Walk over to the Jewish Ghetto, one of Rome’s most fascinating neighborhoods, for lunch at Ba’Ghetto or Nonna Betta, where you can try carciofi alla giudia (Jewish-style fried artichokes).

Afternoon: Visit the Portico of Octavia and stroll along the Tiber River.

Aperitivo: Before dinner, stop by Il Goccetto, a charming wine bar, for a glass of local wine.

Dinner: Dine at Trattoria Pennestri, a modern take on Roman cuisine featuring dishes like oxtail stew and handmade pasta.

Day 3: Vatican City & Trastevere

Morning: Start with a visit to St. Peter’s Basilica, followed by the Vatican Museums and Sistine Chapel. (Book a skip-the-line ticket!)

Lunch: Visit Sorpasso, a stylish yet cozy spot near the Vatican, for a plate of tonnarelli cacio e pepe.

Afternoon: Cross the Tiber and wander through Trastevere, a charming, bohemian district filled with cobblestone streets and hidden gems.

Dinner: Experience Da Enzo al 29, a beloved trattoria serving hearty Roman classics. Be sure to try their burrata with anchovies and amatriciana.

Day 4: Hidden Gems & Testaccio Food Tour

Morning: Visit Campo de’ Fiori, one of Rome’s best open-air markets, followed by a stop at the Palazzo Spada to see Borromini’s optical illusion gallery.

Lunch: Head to Testaccio, the city’s culinary heart, for a food tour exploring the best of Rome’s street food—supplì (fried rice balls), porchetta sandwiches, and maritozzo (sweet cream-filled buns). Testaccio Market is a must-visit!

Afternoon: Explore the Aventine Keyhole for a secret view of St. Peter’s Basilica, then relax at Giardino degli Aranci (Orange Garden), a quiet escape with stunning city views.

Dinner: Enjoy a leisurely meal at Per Me by Giulio Terrinoni, a Michelin-starred restaurant serving creative seafood dishes.

Day 5: Day Trip to Tivoli or Cooking Class

Option 1: Day Trip to Tivoli

• Visit Villa d’Este, a UNESCO World Heritage Site known for its breathtaking fountains and gardens.

• Explore Villa Adriana, the vast Roman retreat of Emperor Hadrian.

• Enjoy lunch at Ristorante Sibilla, a historic restaurant with a terrace overlooking ancient ruins.

Option 2: Cooking Class in Rome

• Learn to make fresh pasta, tiramisu, or traditional Roman dishes with a local chef. Many classes include a market tour!

• Enjoy the meal you prepared with a glass of Italian wine.

Final Aperitivo & Farewell Dinner:

• Toast your Roman adventure with an aperitivo at Hotel de Russie’s Stravinskij Bar or Salotto 42.

• For your last meal, go all out at La Pergola, Rome’s only three-Michelin-starred restaurant, or opt for a more relaxed, yet elegant, dinner at Rimessa Roscioli.

Final Tips for Your Rome Trip

• Book major attractions in advance to avoid long lines.

• Wear comfortable shoes—Rome’s cobblestone streets can be brutal.

• Eat like a local—stick to trattorias and osterias instead of touristy spots.

• Embrace the aperitivo culture—enjoy pre-dinner drinks and snacks to experience Rome like a Roman.

Rome is a city that never ceases to amaze, whether you’re visiting for the first time or the tenth. With this five-day itinerary, you’ll get a perfect balance of history, food, and local culture—ensuring that your time in the Eternal City is nothing short of unforgettable.

Need help planning your trip to Rome? I create custom itineraries tailored to your travel style. Let’s chat!